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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491174Generated: October 31, 2026

1H-Indole, 1-(2,2-dimethyl-1-oxopropyl)- → 2,2-Dimethyl-1-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)propan-1-one

https://huagongshe.com/reaction/1491174

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indole, 1-(2,2-dimethyl-1-oxopropyl)-HCID 839143—
ReagentPinacolHCID 6425—
ReagentBoron tribromideHCID 25134—
Product2,2-Dimethyl-1-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)propan-1-oneHCID 15001912165%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1002/anie.201909786
Source datasetBorylation dataset from Roche
ORD IDord-164577140edc436c99d9264e80008fb8
Source noteBorylation dataset from Roche