1H-Indole, 1-(2,2-dimethyl-1-oxopropyl)- → 2,2-Dimethyl-1-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)propan-1-one

HRID 1491174Notes

Reaction equation

HRID 1491174 reaction equation
CC(C)(C)C(=O)n1ccc2ccccc21>BrB(Br)Br.CC(C)(O)C(C)(C)O>CC(C)(C)C(=O)n1ccc2cccc(B3OC(C)(C)C(C)(C)O3)c21

Participants

4

Reactant 1

HCID 8391431H-Indole, 1-(2,2-dimethyl-1-oxopropyl)-

Product 1

HCID 1500191212,2-Dimethyl-1-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)propan-1-oneYield 65%

Reagents, catalysts & solvents 2

HCID 6425PinacolReagentHCID 25134Boron tribromideReagent

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-164577140edc436c99d9264e80008fb8
Source dataset
Borylation dataset from Roche

Reaction notes

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