1-(5-Iodoindol-1-yl)-2,2-dimethylpropan-1-one → 5-Iodo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-indole

HRID 1491176Notes

Reaction equation

HRID 1491176 reaction equation
CC(C)(C)C(=O)n1ccc2cc(I)ccc21>BrB(Br)Br.CC(C)(O)C(C)(C)O>CC1(C)OB(c2cc(I)cc3cc[nH]c23)OC1(C)C

Participants

4

Reactant 1

HCID 1728653341-(5-Iodoindol-1-yl)-2,2-dimethylpropan-1-one

Product 1

HCID 1015026775-Iodo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-indoleYield 49%

Reagents, catalysts & solvents 2

HCID 6425PinacolReagentHCID 25134Boron tribromideReagent

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-bfca3398fe9b4d56885e24ca837d6240
Source dataset
Borylation dataset from Roche

Reaction notes

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