1,1-Dimethylethyl N-[4-(trifluoromethyl)phenyl]carbamate → HCID 130053536, compound

HRID 1491231Notes

Reaction equation

HRID 1491231 reaction equation
CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCCCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1B1OC(C)(C)C(C)(C)O1

Participants

7

Reactant 1

HCID 112307451,1-Dimethylethyl N-[4-(trifluoromethyl)phenyl]carbamate

Product 1

HCID 130053536HCID 130053536, compoundYield 82%

Reagents, catalysts & solvents 5

HCID 2733548Bis(pinacolato)diboraneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 42491874,4'-Di-tert-butyl-2,2'-bipyridylReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8078CyclohexaneSolvent

Conditions

Temperature
120 °C

Sources & evidence

ORD record
ord-d49877f1b2af4dd6ae22f6f0b3e4fe44
Source dataset
Borylation dataset from Roche

Reaction notes

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