Trifluoroacetic acid → 5-Chloro-6-fluoro-2,3-dihydro-1H-isoindole
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][c:10]1[F:11])[CH2:7][N:6]([C:12]([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[CH2:5]2.[OH:31][C:32]([C:33]([F:34])([F:35])[F:36])=[O:37]>>[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][c:10]1[F:11])[CH2:7][NH:6][CH2:5]2Participants
3
Sources & evidence
- ORD record
- ord-cb7e260d81e14b9f9778acba8d0a996d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…