HCID 178500058, compound → HCID 178500056, compound

HRID 1491452Notes

Reaction equation

HRID 1491452 reaction equation
COC(=O)C(Cc1cn([Si](C(C)C)(C(C)C)C(C)C)c2ccccc12)NC(=O)OC(C)(C)C>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.CCCCCC.C[OH2+].C[OH2+].Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C.[Ir].[Ir]>COC(=O)C(Cc1cn([Si](C(C)C)(C(C)C)C(C)C)c2cc(B3OC(C)(C)C(C)(C)O3)ccc12)NC(=O)OC(C)(C)C.COC(=O)C(Cc1cn([Si](C(C)C)(C(C)C)C(C)C)c2ccc(B3OC(C)(C)C(C)(C)O3)cc12)NC(=O)OC(C)(C)C

Participants

8

Reactant 1

HCID 178500058HCID 178500058, compound

Product 2

HCID 178500056HCID 178500056, compoundYield 59%HCID 178500057HCID 178500057, compoundYield 15%

Reagents, catalysts & solvents 5

HCID 742653,4,7,8-Tetramethyl-1,10-phenanthrolineReagentHCID 2733548Bis(pinacolato)diboraneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8058HexaneSolvent

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-527b263d0626443cb7db7012bb9b3e81
Source dataset
Borylation dataset from Roche

Reaction notes

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