4-Iodobenzoyl chloride → 1-(4-Iodophenyl)-4-propyl-2,6,7-trioxabicyclo[2.2.2]octane

HRID 1491596Notes

Reaction equation

[CH2:1]([C:4]([CH2:9][OH:10])([CH2:7][OH:8])[CH2:5][OH:6])[CH2:2][CH3:3].[I:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](Cl)=O)=[CH:14][CH:13]=1>>[I:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]23[O:10][CH2:9][C:4]([CH2:1][CH2:2][CH3:3])([CH2:7][O:8]2)[CH2:5][O:6]3)=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 743734-Iodobenzoyl chloride

HCID 81928Butylidynetrimethanol

Product 1

HCID 150219581-(4-Iodophenyl)-4-propyl-2,6,7-trioxabicyclo[2.2.2]octane

Procedure

1-(4-Iodophenyl)-4-propyl-2,6,7-trioxabicyclo[2,2,2]octane was prepared from 2-n-propyl-2-hydroxymethyl-propan-1,3-diol and 4-iodobenzoyl chloride using the method described in Example 1 stages (i)-(iii)

Sources & evidence

ORD record: ord-f7f4dca6c15249c3b8b882fd82252c75
Source dataset: uspto-grants-1994_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05371075

Reaction notes

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