HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloropurine → HCID 57145125, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloropurine | HCID 5359277 | — |
| Reactant | (1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol | HCID 10631861 | — |
| Product | HCID 57145125 | HCID 57145125 | 47.9% |
Reaction Steps
Using (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl] ethanol (607 mg) and 6-chloropurine (422 mg), (2S)-2-[(1R)-1-[6-chloro-9(9H) -purinyl]ethyl]-2-(2,4-difluorophenyl) oxirane (440 mg) was obtained as a white powder by the same way as in Reference Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05371100 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-165d17dead1a4e7ba3937cbe11e644e5 |
| Source note | uspto-grants-1994_12 |