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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491821Generated: October 28, 2026

6-(Hydroxymethyl)pyridine-2-carboxamide → HCID 18953918, compound

https://huagongshe.com/reaction/1491821

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(Hydroxymethyl)pyridine-2-carboxamideHCID 14916981—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
ProductHCID 18953918HCID 1895391861.3%

Reaction Steps

A mixture of 6-hydroxymethyl-2-pyridinecarboxamide (100 g) and manganese dioxide (500 g) in chloroform (2 l) was heated under reflux for 48 hours. Manganese dioxide was removed by filtration and the filtrate was evaporated in vacuo to give 6-formyl-2-pyridinecarboxamide (60.46 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05371097
Source datasetuspto-grants-1994_12
ORD IDord-0d14b8dd3316448dab3144b334b45322
Source noteuspto-grants-1994_12