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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491853Generated: October 30, 2026

HCID 18953815, compound → HCID 18953827, compound

https://huagongshe.com/reaction/1491853

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18953815HCID 18953815—
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
SolventMethanolHCID 887—
ProductHCID 18953827HCID 18953827—

Reaction Steps

A suspension of 4-[2-(diaminomethyleneamino)thiazol-4-yl ]thiazole-2-carboxamide (1.0 g) in 4N-hydrogenchloride/dioxane (1.0 ml) and methanol (10 ml) was stirred for 1 hour at room temperature. The resulting precipitate was collected by filtration. Recrystallization from water afforded 4-[2-(diaminomethyleneamino)thiazol-4-yl)thiazole-2-carboxamide hydrochloride (850 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05371097
Source datasetuspto-grants-1994_12
ORD IDord-fe1c5d6e612d4f2a8ea845d384b20d09
Source noteuspto-grants-1994_12