Hydrochloric Acid → HCID 18953926, compound

Participants

Reaction Steps

Hydrogen chloride gas was babbled to a solution of 4-[2-(2-t-butoxycarbonylaminoethyl)thiazol-4-yl]-2-(diaminomethyleneamino)thiazole (3.0 g) in ethanol (30 ml) for 10 minutes at room temperature. The mixture was stirred at room temperature for 20 minutes. The resulting precipitate was collected by filtration. Recrystallization from a mixture of methanol and diisopropyl ether afforded 4-[2-(2-aminoethyl)thiazol-yl]-2-(diaminomethyleneamino)thiazole dihydrochloride (2.3 g).

Provenance & Evidence