HCID 178435512, compound → HCID 178435511, compound

Participants

Reaction Steps

A solution of 1 g of 7-ethyl-1,2-dihydro-4-methyl-3-o-nitrobenzyl-2-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]quinoline in 25 ml of ethanol is hydrogenated on 0.3 g of 5% Pd-on-charcoal at 20° and normal pressure until the calculated amount of H2 has been taken up. The catalyst is filtered off, the filtrate is evaporated and the 3-o-aminobenzyl-7-ethyl-1,2-dihydro-4-methyl-2-oxo-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-yl-methyl]quinoline obtained is purified by chromatography.

Provenance & Evidence