Phosphorus oxychloride → 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Reaction equation
[CH:1]1([n:4]2[cH:5][c:6]([C:17](=[O:18])[OH:19])[c:7](=[O:16])[c:8]3[cH:9][c:10]([F:15])[c:11]([OH:14])[n:12][c:13]23)[CH2:2][CH2:3]1.[P:20]([Cl:21])([Cl:22])([Cl:23])=[O:24]>>[CH:1]1([n:4]2[cH:5][c:6]([C:17](=[O:18])[OH:19])[c:7](=[O:16])[c:8]3[cH:9][c:10]([F:15])[c:11]([Cl:22])[n:12][c:13]23)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-10614076f6f948309e1bf0203cc71689
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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