HCID 14209946, compound → HCID 14476479, compound

HRID 1492168Notes

Reaction equation

HRID 1492168 reaction equation
[CH3:1][C:2]1([CH3:16])[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([N+:12]([O-])=O)[CH:10]=2)[NH:5][C:4](=[O:15])[CH2:3]1>[Pd].CO>[NH2:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[NH:5][C:4](=[O:15])[CH2:3][C:2]2([CH3:16])[CH3:1]

Participants

4

Reactant 1

HCID 14209946HCID 14209946, compound

Product 1

HCID 14476479HCID 14476479, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

22 g. (0.1 mole) 1,2,3,4-tetrahydro-4,4-dimethyl-6-nitroquinolin-2-one in 500 ml. methanol are, after the addition of 2 g. palladium on charcoal (10%), hydrogenated at atmospheric pressure. After separating off the catalyst, the solvent is removed in a vacuum. Yield 18.4 g. (97% of theory); m.p. 126°-130° C.

Workup

  1. additionafter the addition of 2 g
  2. customAfter separating off the catalyst
  3. customthe solvent is removed in a vacuum

Sources & evidence

ORD record
ord-6576544c2b5643dea1b093d7a38d5f97
Source dataset
uspto-grants-1994_12
Patent number
US05373019

Reaction notes

Loading…