HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Piperidone → HCID 178478132, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Piperidone | HCID 12665 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 18952306 | HCID 18952306 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 178478132 | HCID 178478132 | — |
Reaction Steps
A mixture of 2-piperidone (6 g) in benzene (50 ml), 4-(2-amino-4-chlorobenzyl)morpholine (6.8 g) in benzene (50 ml) and phosphorus oxychloride (5.5 ml) was heated at 60°-65° C. for 5 hours to give 4-[4-chloro-2-(2-piperidinylideneamino)benzyl]morpholine (m.p. 121°-122° C.) which was recrystallised from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05373008 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-2fa0f63fbe0a4e0cbd8430e645ed8505 |
| Source note | uspto-grants-1994_12 |