Phosphorus oxychloride → HCID 15746360, compound

HRID 1492206Notes

Reaction equation

HRID 1492206 reaction equation
[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][O:9][C:10](=[O:12])[CH3:11])[C:3]1=O.[NH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N:21]1[CH2:26][CH2:25][O:24][CH2:23][CH2:22]1.P(Cl)(Cl)(Cl)=O>C1C=CC=CC=1>[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][O:9][C:10](=[O:12])[CH3:11])[C:3]1=[N:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N:21]1[CH2:26][CH2:25][O:24][CH2:23][CH2:22]1

Participants

5

Reactant 3

HCID 24813Phosphorus oxychlorideHCID 7357562-MorpholinoanilineHCID 15746399HCID 15746399, compound

Product 1

HCID 15746360HCID 15746360, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

Reaction of 1-methyl-3-(2-acetoxyethyl)-2-imidazolidinone (13.4 g) in benzene (80 ml) with 4-(2-aminophenyl)morpholine (10.6 g) in benzene (80 ml) in the presence of phosphorus oxychloride (7 ml) for 30 hours at 80°-85° C. gave 4-{2-[1-methyl-3-(2-acetoxyethyl)-2-imidazolidinylideneamino]phenyl}morpholine.

Sources & evidence

ORD record
ord-c79ca38146fd49f2b83e4579ba340601
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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