HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 15746465, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-Morpholinoaniline | HCID 735756 | — |
| Reactant | N,N-dimethylmorpholine-4-carboxamide | HCID 3411496 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 15746465 | HCID 15746465 | — |
Reaction Steps
Reaction of 4-dimethylcarbamoylmorpholine (3.8 g) in benzene (25 ml) with 4-(2-aminophenyl)morpholine (3.5 g) in the presence of phosphorus oxychloride (2.1 ml) for 40 hours at 80°-85° C. gave N,N-dimethyl-N'-(2-morpholinophenyl)morpholine-4-carboxamidine (m.p. 126°-128° C.) which was recrystallised from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05373008 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-1e28973a11e54a50a0b73bd272a63bde |
| Source note | uspto-grants-1994_12 |