Methyl iodide → HCID 178495928, compound

HRID 1492218Notes

Reaction equation

HRID 1492218 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]([CH2:16][CH2:17][O:18][CH3:19])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:12][C:13]([NH2:15])=[S:14].[CH3:20][I:21]>CC(C)=O>[IH:21].[CH3:20][S:14][C:13](=[NH:15])[NH:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[N:5]([CH2:4][CH2:3][O:2][CH3:1])[CH2:16][CH2:17][O:18][CH3:19]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 15746480HCID 15746480, compound

Product 1

HCID 178495928HCID 178495928, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Conditions

Temperature
40 °C

Procedure

A mixture of 1-{2-[bis(2-methoxyethyl)amino]phenyl}thiourea (5 g), methyl iodide (1.4 ml) and acetone (25 ml) was heated at 40° C. for 2 hours. Removal of the solvent gave a residue which was triturated with ether to give 2-methyl-1-{2-[bis(2-methoxyethyl)amino]phenyl}-2-thiopseudourea hydroiodide (m.p. 111°-112° C.).

Workup

  1. customRemoval of the solvent
  2. customgave a residue which
  3. customwas triturated with ether

Sources & evidence

ORD record
ord-087d4d657a124137b2a097342619ab69
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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