Methyl iodide → HCID 178503987, compound

HRID 1492222Notes

Reaction equation

HRID 1492222 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[C:6]([NH:8][C:9]([NH2:11])=[S:10])[CH:7]=1.[CH3:18][I:19]>CO>[IH:19].[CH3:18][S:10][C:9](=[NH:11])[NH:8][C:6]1[CH:7]=[C:2]([CH3:1])[CH:3]=[CH:4][C:5]=1[N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 18952152HCID 18952152, compound

Product 1

HCID 178503987HCID 178503987, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 1-(5-methyl-2-morpholinophenyl)thiourea (14 g), methyl iodide (7.9 g) in methanol (50 ml) was heated at reflux for 2 hours to give 2-methyl-1-(5-methyl-2-morpholinophenyl)-2-thiopseudourea hydroiodide as a pale yellow solid, m.p. 157°-159° C.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 2 hours

Sources & evidence

ORD record
ord-b7c93cb6acda43b8a31b064147941c23
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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