Sodium Hydroxide → HCID 15746488, compound

Participants

Reaction Steps

A mixture of 1-benzoyl-3-[2-(2-methyl-1-pyrrolidinyl)phenyl]thiourea (9 g), sodium hydroxide (1 g, as pellets) and water (10 ml) was heated at 90°-95° C. for 48 hours to give 1-[2-(2-methyl-1-pyrrolidinyl)phenyl]thiourea (m.p. 145°-148° C.) which was purified by column chromatography on silica gel using a 1:1 mixture of ethylacetate and hexane as eluant.

Provenance & Evidence