Propylenediamine → HCID 178430622, compound

Participants

Reaction Steps

A mixture of 2-methyl-1-(2-morpholinophenyl)-2-thiopseudourea hydroiodide (3.8 g prepared as described in Example 166), 2-methylethylenediamine (2.2 g) and ethanol (45 ml) was heated under reflux for 8 hours to give a solid which was recrystallised from ethyl acetate to give 4-[2-(4-methyl-2-imidazolidinylideneamino)phenyl]morpholine (m.p. 173°-174° C.).

Provenance & Evidence