Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 18952330 | HCID 18952330 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178464551 | HCID 178464551 | — |
Reaction Steps
A mixture of 2-methyl-3-ethyl-1-(2-morpholinophenyl)-2-thiopseudourea hydroiodide (6 g) and 33% methylamine in absolute ethanol solution (250 ml) was heated initially for 24 hours at 45° C. and then left at room temperature for 14 days to yield 1-ethyl-2-(2-morpholinophenyl)-3-methylguanidine as a colourless solid (m.p. 118°-119° C.) which was recrystallised from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05373008 |
|---|
| Source dataset | uspto-grants-1994_12 |
|---|
| ORD ID | ord-2891a53ae8454b7ebbff41aecb70e14e |
|---|
| Source note | uspto-grants-1994_12 |
|---|
