Methyl iodide → HCID 18952165, compound

HRID 1492257Notes

Reaction equation

HRID 1492257 reaction equation
[CH3:1][NH:2][C:3]([NH:5][C:6]1[CH:11]=[C:10]([CH3:12])[CH:9]=[CH:8][C:7]=1[N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1)=[S:4].[CH3:19][I:20]>CC(C)=O>[IH:20].[CH3:19][S:4][C:3](=[N:2][CH3:1])[NH:5][C:6]1[CH:11]=[C:10]([CH3:12])[CH:9]=[CH:8][C:7]=1[N:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 18952224HCID 18952224, compound

Product 1

HCID 18952165HCID 18952165, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 1-methyl-3-(5-methyl-2-morpholinophenyl)thiourea (6.4 g) and methyl iodide (3.8 g) in acetone (60 ml) was heated at reflux for 4 hours to give 2-methyl-1-(5-methyl-2-morpholinophenyl)-3-methyl-2-thiopseudourea hydroiodide as a pale yellow solid (m.p. 160°-161° C.).

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 4 hours

Sources & evidence

ORD record
ord-7ef48c19716d4b75bfc96073dffe60fb
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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