HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178426250, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | N-(2-Hydroxyethyl)ethylenediamine | HCID 8112 | — |
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | HCID 18952165 | HCID 18952165 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178426250 | HCID 178426250 | — |
Reaction Steps
A mixture of 2-methyl-1-(5-methyl-2-morpholinophenyl)-3-methyl-2-thiopseudourea hydroiodide (8.4 g prepared as described in Example 227), N-(2-hydroxyethyl)ethylenediamine (6.8 ml) and ethanol (80 ml)) was heated under reflux for 30 hours to give an oil which was treated with fumaric acid in methanol to give 4-{2-[1-(2-hydroxyethyl)-2-imidazolidinylideneamino]-4-methylphenyl}morpholine sesquifumarate (m.p. 135°-136° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05373008 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-05de5f274f0e4bf2af42489cf9c3756c |
| Source note | uspto-grants-1994_12 |