Potassium Hydroxide → HCID 18952323, compound

HRID 1492281Notes

Reaction equation

HRID 1492281 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[C:6]([NH:8][C:9]([NH2:11])=S)[CH:7]=1.O.O.O.C([O-])(=O)C.[Pb+2].C([O-])(=O)C.[OH-].[K+]>O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[C:6]([NH:8][C:9]#[N:11])[CH:7]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 22456Lead diacetate trihydrateHCID 18952243HCID 18952243, compound

Product 1

HCID 18952323HCID 18952323, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent3×

Procedure

A mixture of 1-(5-chloro-2-morpholinophenyl) thiourea (5.97 g) suspended in water (40 ml), lead acetate trihydrate (8.75 g) in water (40 ml) and potassium hydroxide (12.6 g) in water (35 ml) was heated under reflux for 15 minutes to give N-(5-chloro-2-morpholinophenyl)cyanamide as a white solid (m.p. 305°-308° C.).

Workup

  1. temperatureunder reflux for 15 minutes

Sources & evidence

ORD record
ord-0610919ccddb4761b9f614766bd68ed0
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

Loading…