Sulfuric Acid → HCID 131718012, compound

HRID 1492298Notes

Reaction equation

HRID 1492298 reaction equation
[CH3:1][N:2]([CH3:18])[C:3]([NH2:17])=[N:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1.[S:19](=[O:23])(=[O:22])([OH:21])[OH:20]>CC(C)=O>[S:19]([OH:23])([OH:22])(=[O:21])=[O:20].[CH3:1][N:2]([CH3:18])[C:3]([NH2:17])=[N:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1.[CH3:1][N:2]([CH3:18])[C:3]([NH2:17])=[N:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 98854071,1-Dimethyl-2-(2-morpholinophenyl)guanidine

Product 1

HCID 131718012HCID 131718012, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Reaction of the product of Example 301 in acetone with concentrated sulphuric acid gave 1,1-dimethyl-2-(2-morpholinophenyl)guanidine hemisulphate (m.p. 234°-235° C.) which was recrystallised from a 1:1 mixture of methanol and ether.

Sources & evidence

ORD record
ord-b23ad22044614385b40293ab0f64fd63
Source dataset
uspto-grants-1994_12
Patent number
US05373008

Reaction notes

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