Hydrochloric Acid → Methyl 2-aminoisobutyrate hydrochloride

HRID 1492396Notes

Reaction equation

HRID 1492396 reaction equation
[NH2:1][C:2]([CH3:7])([CH3:6])[C:3]([OH:5])=[O:4].[ClH:8].[CH3:9]O>>[ClH:8].[CH3:9][O:4][C:3](=[O:5])[C:2]([NH2:1])([CH3:7])[CH3:6]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887Methanol2×HCID 6119Aminoisobutyric acid

Product 1

HCID 13258034Methyl 2-aminoisobutyrate hydrochloride

Procedure

To 2-aminoisobutyric acid in 125 ml of methanol is added 125 ml of methanol saturated with HCl. The initial mixture becomes a solution and the reaction is sealed and allowed to stir at room temperature overnight. The next day the reaction is evaporated, first neat and then from toluene to give a solid.

Workup

  1. customthe reaction is sealed
  2. customThe next day the reaction is evaporated
  3. customfirst neat and then from toluene to give a solid

Sources & evidence

ORD record
ord-76a032d338d6441d88a27f985e2cdf2a
Source dataset
uspto-grants-1994_12
Patent number
US05374623

Reaction notes

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