Sulfuric Acid → HCID 18950756, compound

Participants

Reaction Conditions

Reaction Steps

To 0.38 g of methyl 4-[2-formamido-2-(3-pyridyl)ethyl]phenylacetate in 10 ml of methanol-1,4 dioxane (1:1) in solution was added 5 ml of 4% sulfuric acid, and stirred under heating at 60° C. for one hour, which was then poured into saturated aqueous sodium chloride solution for extraction with ethyl acetate. The ethyl acetate phase obtained was washed in saturated aqueous sodium chloride solution and dried over magnesium sulfate, followed by distillation of the solvent, to produce 0.11 g of methyl 4-[2-amino-2-(3-pyridyl)ethyl]phenylacetate.

Provenance & Evidence