Hydrochloric Acid → HCID 18950749, compound

Participants

Reaction Steps

To 20 ml of the solution of 0.14 g of methyl 4-[3-(4-chlorobenzenesulfonamido)-3-(3-pyridyl)propyl}benzoate in methanol-1,4 dioxane (1:1) was added 5 ml of aqueous 2N sodium hydroxide solution, and stirred at room temperature overnight. After completion of the reaction followed by neutralization with 5 ml of 2N hydrogen chloride, the crystalline deposited was filtered to obtain 72 mg of 4-[3-(4-chlorobenzenesulfonamido)-3-(3-pyridyl)propyl]benzoic acid. The spectrometric data supports the structure of [37] as follows.

Provenance & Evidence