HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethyl-8-ethyl-1-deazapurine → 3-[4-(1-carbomethoxy-1-phenylmethoxy)-3,5-dichlorophenylmethyl]-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethyl-8-ethyl-1-deazapurine | HCID 9815374 | — |
| Reactant | Methyl 2-(4-bromomethyl-2,6-dichlorophenoxy)-2-phenylacetate | HCID 19385677 | — |
| Product | 3-[4-(1-carbomethoxy-1-phenylmethoxy)-3,5-dichlorophenylmethyl]-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]-pyridine | HCID 19385591 | 68% |
Reaction Steps
The product of Step E (0.126 g, 0.31 mmol) was used to alkylate 0.050 g (0.29 mmol) of 5,7-dimethyl-2-ethylimidazo[4,5-b]pyridine according to the procedure described for Step B of Example 2, which after purification afforded 0.096 g (68%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05374638 |
| Source dataset | uspto-grants-1994_12 |
| ORD ID | ord-eb540c4f4a854cac9f9c756af1fb9492 |
| Source note | uspto-grants-1994_12 |