HRID1492923

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2774217

Ethanamine, 2-bromo-, hydrobromide (1:1)

C2H7Br2N

HCID7176209

5-chloro-2-formylbenzoic acid

C8H5ClO3

PRODUCTS

生成物

HCID18949893

2-(2-Bromoethyl)-5-chloro-2,3-dihydro-3-hydroxy-1H-isoindol-1-one

C10H9BrClNO2

收率 27.8%

PROCEDURE

实验过程

The compound was prepared as described in example 1A, starting from 2.5 g (0.013 mole) of 4-chloro-2-carboxybenzaldehyde (I1 farmaco, Ed. Sci 31, 691, 1976) and 2.76 g (0.013 mole) of 2-bromoethylamine hydrobromide. 1.05 g of the title product were obtained; mp=164°-168 ° C. (n-hexane).

WORKUP

后处理

customThe compound was prepared