Hydrochloric Acid → Benzenecarboximidic acid, 3-acetyl-, ethyl ester, hydrochloride

HRID 1492959Notes

Reaction equation

HRID 1492959 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[C:7]#[N:8])(=[O:3])[CH3:2].[ClH:12].[CH3:13][CH2:14][O:15]CC>C(O)C>[ClH:12].[CH2:14]([O:15][C:7](=[NH:8])[C:6]1[CH:9]=[CH:10][CH:11]=[C:4]([C:1](=[O:3])[CH3:2])[CH:5]=1)[CH3:13]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 802223-Acetylbenzonitrile

Product 1

HCID 12289426Benzenecarboximidic acid, 3-acetyl-, ethyl ester, hydrochloride

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 7.25 g (0.05 mol) of 3-acetylbenzonitrile in 150 ml of ether and 4.5 ml of ethanol is saturated at 0° with dry hydrochloric acid gas and then left to stand at 0° for 2 days. The product which crystallises out is filtered off and recrystallised from ethanol/ether; m.p. 110° (with decomposition).

Workup

  1. waitleft
  2. customThe product which crystallises out
  3. filtrationis filtered off
  4. customrecrystallised from ethanol/ether

Sources & evidence

ORD record
ord-3d6dee616b004fa2a3ff1ac07c9648b0
Source dataset
uspto-grants-1994_12
Patent number
US05376685

Reaction notes

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