Ammonium Chloride → HCID 178433667, compound

HRID 1493338Notes

Reaction equation

HRID 1493338 reaction equation
C(NC(N)=N)#N.[Cl-].[NH4+].Cl.Cl.Cl.[NH:12]1[CH:16]=[C:15]([CH2:17][CH2:18][CH2:19][NH:20][C:21]([NH:23][CH2:24][CH:25]([S:27][CH2:28][C:29]2[N:30]=[CH:31][NH:32][C:33]=2[CH3:34])[CH3:26])=[NH:22])[N:14]=[CH:13]1>Cl>[NH:12]1[CH:16]=[C:15]([CH2:17][CH2:18][CH2:19][NH:20][C:21]([NH:23][CH2:24][CH:25]([S:27][CH2:28][C:29]2[N:30]=[CH:31][NH:32][C:33]=2[CH3:34])[CH3:26])=[NH:22])[N:14]=[CH:13]1

Participants

5

Reactant 3

HCID 25517Ammonium ChlorideHCID 178418324HCID 178418324, compoundHCID 178433668HCID 178433668, compound

Product 1

HCID 178433667HCID 178433667, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

0.76 g (1.92 mmol) of the previously prepared cyanoguanidine is heated under reflux for 2 hours in 30 ml of 18% hydrochloric acid. Concentration of the reaction mixture by evaporation under vacuum leaves 0.96 g of hygroscopic foam composed of equimolar quantities of ammonium chloride and N-[3-(imidazol-4-yl)propyl]-N'-[2-[(5-methylimidazol-4-yl)methylthio]-1-propyl]-guanidine trihydrochloride.

Workup

  1. customConcentration of the reaction mixture by evaporation under vacuum
  2. customleaves 0.96 g of hygroscopic foam

Sources & evidence

ORD record
ord-97f1da4b409b4796b559e59788f696ad
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

Loading…