HCID 178523921, compound → HCID 178512142, compound

HRID 1493342Notes

Reaction equation

HRID 1493342 reaction equation
C([NH:9][C:10]([NH:21][CH2:22][CH2:23][CH2:24][C:25]1[N:26]=[CH:27][NH:28][CH:29]=1)=[N:11][CH2:12][CH2:13][S:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(=O)C1C=CC=CC=1>Cl>[NH:28]1[CH:29]=[C:25]([CH2:24][CH2:23][CH2:22][NH:21][C:10]([NH:11][CH2:12][CH2:13][S:14][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[NH:9])[N:26]=[CH:27]1

Participants

3

Reactant 1

HCID 178523921HCID 178523921, compound

Product 1

HCID 178512142HCID 178512142, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

0.82 g (2 mmol) of N-benzoyl-N'-[3-(imidazol 4-yl) propyl]-N"-(2-phenylthioethyl)-guanidine are heated under reflux in 18% hydrochloric acid for 7 hours and then worked up by a method analogous to that of Example 58. 0.72 g (96%) of a dry, hygroscopic foam is obtained.

Workup

  1. custom0.72 g (96%) of a dry, hygroscopic foam is obtained

Sources & evidence

ORD record
ord-ab311f9414554f27866bb976d6f51031
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

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