HCID 178523917, compound → HCID 178512196, compound

HRID 1493343Notes

Reaction equation

HRID 1493343 reaction equation
C([NH:9][C:10]([NH:22][CH2:23][CH2:24][CH2:25][C:26]1[N:27]=[CH:28][NH:29][CH:30]=1)=[N:11][CH2:12][CH2:13][CH2:14][S:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=O)C1C=CC=CC=1>Cl>[NH:29]1[CH:30]=[C:26]([CH2:25][CH2:24][CH2:23][NH:22][C:10]([NH:11][CH2:12][CH2:13][CH2:14][S:15][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[NH:9])[N:27]=[CH:28]1

Participants

3

Reactant 1

HCID 178523917HCID 178523917, compound

Product 1

HCID 178512196HCID 178512196, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

0.84 g (2 mmol) of N-benzoyl-N'-[3-(imidazol-4-yl) propyl]-N"-(3-phenylthiopropyl)-guanidine are heated under reflux in 18% hydrochloric acid for 7 hours and then worked up by a method analogous to that of Example 58. 0.71 g (91%) of a dry, hygroscopic foam is obtained.

Workup

  1. custom0.71 g (91%) of a dry, hygroscopic foam is obtained

Sources & evidence

ORD record
ord-f1031ee7ee9d4d2ba1de05a0c1baffa2
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

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