HCID 178523909, compound → HCID 178512145, compound

HRID 1493344Notes

Reaction equation

HRID 1493344 reaction equation
C([NH:9][C:10]([NH:22][CH2:23][CH2:24][CH2:25][C:26]1[N:27]=[CH:28][NH:29][CH:30]=1)=[N:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=O)C1C=CC=CC=1>Cl>[NH:29]1[CH:30]=[C:26]([CH2:25][CH2:24][CH2:23][NH:22][C:10]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[NH:9])[N:27]=[CH:28]1

Participants

3

Reactant 1

HCID 178523909HCID 178523909, compound

Product 1

HCID 178512145HCID 178512145, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

0.8 g (2 mmol) of N-benzoyl-N'-[3-(imidazol-4-yl) propyl]-N"-(4-phenylbutyl)-guanidine are heated under reflux in 45 ml of 20% hydrochloric acid for 7 hours and then worked up by a method analogous to that of Example 58. 0.60 g (81%) of a highly hygroscopic, noncrystalline solid is obtained.

Workup

  1. custom0.60 g (81%) of a highly hygroscopic, noncrystalline solid is obtained

Sources & evidence

ORD record
ord-09dfa053967c49f39ed544350026f95f
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

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