HCID 178523907, compound → HCID 178512143, compound

HRID 1493348Notes

Reaction equation

HRID 1493348 reaction equation
C([NH:9][C:10]([NH:20][CH2:21][CH2:22][S:23][CH2:24][C:25]1[CH:34]=[CH:33][C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[N:26]=1)=[N:11][CH2:12][CH2:13][CH2:14][C:15]1[N:16]=[CH:17][NH:18][CH:19]=1)(=O)C1C=CC=CC=1>Cl>[N:26]1[C:27]2[C:32](=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:33]=[CH:34][C:25]=1[CH2:24][S:23][CH2:22][CH2:21][NH:20][C:10]([NH:11][CH2:12][CH2:13][CH2:14][C:15]1[N:16]=[CH:17][NH:18][CH:19]=1)=[NH:9]

Participants

3

Reactant 1

HCID 178523907HCID 178523907, compound

Product 1

HCID 178512143HCID 178512143, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

0.95 g (2 mmol) of N-benzoyl-N'-[2-[(quinolin-2-yl) methylthio]ethyl]-N"-[3-(imidazol-4-yl)propyl]-guanidine are heated under reflux in 45 ml of 18% hydrochloric acid for 6 hours and the product is worked up by a method analogous to that of Example 109. 0.86 g (90%) of a hygroscopic, non-crystalline solid is obtained.

Workup

  1. custom0.86 g (90%) of a hygroscopic, non-crystalline solid is obtained

Sources & evidence

ORD record
ord-e98f1332922a4d79b131038178d3e4d7
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

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