HCID 178523908, compound → HCID 178512144, compound

HRID 1493349Notes

Reaction equation

HRID 1493349 reaction equation
[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]=1[CH2:10][S:11][CH2:12][CH2:13][NH:14][C:15]([NH:25]C(=O)C1C=CC=CC=1)=[N:16][CH2:17][CH2:18][CH2:19][C:20]1[N:21]=[CH:22][NH:23][CH:24]=1>Cl>[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]=1[CH2:10][S:11][CH2:12][CH2:13][NH:14][C:15]([NH:16][CH2:17][CH2:18][CH2:19][C:20]1[N:21]=[CH:22][NH:23][CH:24]=1)=[NH:25]

Participants

3

Reactant 1

HCID 178523908HCID 178523908, compound

Product 1

HCID 178512144HCID 178512144, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

0.65 g (1.4 mmol) of N-[2-[(benzimidazol-2-yl) methylthio]ethyl]-N'-benzoyl-N"-[3-(imidazol-4-yl)propyl]-guanidine are heated under reflux in 45 ml of 18% hydrochloric acid for 6 hours and worked up by a method analogous to that of Example 109.

Sources & evidence

ORD record
ord-ec316d178bc644f782b02be2ae4ce3f8
Source dataset
uspto-grants-1991_06
Patent number
US05021431

Reaction notes

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