HCID 178523918, compound → HCID 178512197, compound

Participants

Reaction Steps

0.84 g (2 mmol) of N-benzoyl-N'[3-(imidazol-4-yl) propyl]-N"-[3-[(pyrid-2-yl)thio]propyl]-guanidine are heated under reflux in 45 ml of 20% hydrochloric acid for 6 hours. The reaction product is worked up by a method analogous to that of Example 109. It initially precipitates as a dry, hygroscopic foam but this foam gradually crystallises when triturated with acetone and a few drops of ethanol.

Provenance & Evidence