Hydrochloric Acid → HCID 13061858, compound

HRID 1493353Notes

Reaction equation

HRID 1493353 reaction equation
[CH3:1][C:2]1[C:3]([O:12][CH3:13])=[C:4]([C:8]([O:10]C)=[O:9])[S:5][C:6]=1[CH3:7].Cl>[OH-].[Na+]>[CH3:13][O:12][C:3]1[C:2]([CH3:1])=[C:6]([CH3:7])[S:5][C:4]=1[C:8]([OH:10])=[O:9]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14154178Methyl 3-methoxy-4,5-dimethyl-2-thiophenecarboxylate

Product 1

HCID 13061858HCID 13061858, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Methyl 4,5-dimethyl-3-methoxythiophene-2-carboxylate (34 g) was heated under reflux in 1M sodium hydroxide solution (500 ml) for 1 hour. After cooling the mixture was acidified with concentrated hydrochloric acid to pH4. The solid was filtered, washed with water and dried, m.p. 142°-143° C.

Workup

  1. temperatureAfter cooling the mixture
  2. filtrationThe solid was filtered
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-59d63cedf5744082af887b37b0f2b888
Source dataset
uspto-grants-1991_06
Patent number
US05021449

Reaction notes

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