HuagongsheHuagongshe Chemistry Print Report · For research reference only
Solketal → 4-[(2,2-dimethyl-1,3-dioxolan-4-yl)-methoxycarbonyl]-(S,S)-2,4-dibenzylbutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Solketal | HCID 7528 | — |
| Reactant | (S,S)-2,4-dibenzylglutaric anhydride | HCID 14557658 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-[(2,2-dimethyl-1,3-dioxolan-4-yl)-methoxycarbonyl]-(S,S)-2,4-dibenzylbutyric acid | HCID 14997152 | — |
Reaction Steps
A solution of 1.0 g of (S,S)-2,4-dibenzylglutaric anhydride and 0.54 g of 4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane in 10 ml of toluene is refluxed overnight. The solution is washed with water, dried (Na2SO4), filtered and concentrated to give 4-[(2,2-dimethyl-1,3-dioxolan-4-yl)-methoxycarbonyl]-(S,S)-2,4-dibenzylbutyric acid as a viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05021430 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-83374060f78843b0a709070dc9fbf14b |
| Source note | uspto-grants-1991_06 |