反应详情

0.19 Gram of 2-propionyl-5-[2-(4-trifluoromethylphenylthio)ethyl]cyclohexane-1,3-dione was dissolved in 5 ml of ethanol, and 0.07 g of allyloxyamine hydrochloride and 0.06 g of triethylamine were added to the resulting solution which was then stirred overnight at room temperature. The reaction solution was poured into water, acidified and extracted with chloroform. After removing chloroform, the residue was purified by thin layer chromatography (eluent, hexane:ethyl acetate=5:1) to obtain 0.13 g of 2-(1-allyloxyaminopropylidene)5-[2-(4-trifluoromethylphenylthio)ethyl]cyclohexane-1,3-dione.

1. extractionextracted with chloroform
2. customAfter removing chloroform
3. customthe residue was purified by thin layer chromatography (eluent, hexane:ethyl acetate=5:1)