Phenoxyacetic Acid → HCID 86744749, compound

HRID 1493710Notes

Reaction equation

HRID 1493710 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:9][NH:10][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:8])=[CH:3][CH:2]=1.[O:16]([CH2:23][C:24]([OH:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C(O)C>[O:16]([CH2:23][C:24]([OH:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:9][NH:10][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:8])=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 19188Phenoxyacetic AcidHCID 53879071HCID 53879071, compound2×

Product 1

HCID 86744749HCID 86744749, compoundYield 66%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 8.2 gm (0.04 mole) of butyric acid [1-4-pyridinyl)ethylidene]hydrazide (Compound 144), 6.09 gm (0.04 mole) of phenoxyacetic acid and 100 ml of absolute ethanol is refluxed 7.5 hr. The reaction mixture is evaporated to dryness in vacuo. The solid is crystallized from ethanol to yield 9.48 gm (66%) of the title compound having a melting point of 105.8° C.

Workup

  1. temperatureis refluxed 7.5 hr
  2. customThe reaction mixture is evaporated to dryness in vacuo
  3. customThe solid is crystallized from ethanol

Sources & evidence

ORD record
ord-cc01044d45bf46a389a7fb2a78c47f1d
Source dataset
uspto-grants-1991_06
Patent number
US05023334

Reaction notes

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