Butyrohydrazide → HCID 86152458, compound

HRID 1493719Notes

Reaction equation

HRID 1493719 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][N:7]=[CH:6][C:5]=1[Cl:10])(=O)[CH3:2].[C:11]([NH:16][NH2:17])(=[O:15])[CH2:12][CH2:13][CH3:14]>C(O)C>[Cl:10][C:5]1[CH:6]=[N:7][CH:8]=[CH:9][C:4]=1[C:1](=[N:17][NH:16][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:2]

Participants

4

Reactant 2

HCID 77079ButyrohydrazideHCID 127424671-(3-Chloropyridin-4-yl)ethan-1-one

Product 1

HCID 86152458HCID 86152458, compoundYield 25%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 5.20 gm (0.0335 mole) of 4-acetyl-3-chloropyridine, 3.43 gm (0.0336 mole) of butyric acid hydrazide and 100 ml of ethanol was refluxed 18 hr. The mixture was chilled in the freezer. The solid which separated was collected to give 2.01 gm (25%) of white solid having a melting point of 103.8° C.

Workup

  1. temperaturewas refluxed 18 hr
  2. temperatureThe mixture was chilled in the freezer
  3. customThe solid which separated
  4. customwas collected

Sources & evidence

ORD record
ord-117de7e8f9e74e56a1aa4df5aa72cbf8
Source dataset
uspto-grants-1991_06
Patent number
US05023334

Reaction notes

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