反应详情

After 24 hours, a GC/MS of the mixture allows identification of all the reaction components. After 72 hours, the reaction seems to stop proceeding while excess diiodobiphenyl remains: another batch of iodotrifluoroethylene (25.0 g, 0.12 mole) is reacted with zinc in THF and added to the reaction mixture along with 1.0 g of palladium tetrakis(triphenylphosphine) catalyst. The reaction is allowed to stir an additional 12 hours, then is removed and evaporated to dryness under high vacuum on a rotary evaporator. Residue from evaporation is added to a 3 fold volumetric excess of water. A heavy precipitate is formed which is filtered and air dried on a vacuum funnel. The precipitate is dissolved in THF and filtered. The resulting filtrate is coated on silica gel by adding the silica gel to the THF solution and evaporating to dryness. This silica gel is then eluted on a short silica gel column using hexane as eluent to remove the colored material from the product. A fine white crystalline material remains after evaporation of the hexane. This crystalline material is then chromatographed again carefully on an alumina column using hexane as an eluent. The first band to elute from the column is the desired monomer product CF2 =CF--Ph--Ph--CF=CF2. A total of 44.2 g of product is recovered (58.7% yield).

1. customthe reaction components
2. waitAfter 72 hours
3. customis removed
4. customevaporated to dryness under high vacuum on a rotary evaporator
5. customResidue from evaporation
6. additionis added to a 3 fold volumetric excess of water
7. customA heavy precipitate is formed which
8. filtrationis filtered
9. customair dried on a vacuum funnel
10. dissolutionThe precipitate is dissolved in THF
11. filtrationfiltered
12. additionby adding the silica gel to the THF solution
13. customevaporating to dryness
14. washThis silica gel is then eluted on a short silica gel column
15. customto remove the colored material from the product
16. customafter evaporation of the hexane
17. customThis crystalline material is then chromatographed again carefully on an alumina column
18. washThe first band to elute from the column
19. customA total of 44.2 g of product is recovered (58.7% yield)