反应详情

A slurry of 38.6 g (0.25 mole) of o-(2-hydroxyethyl)resorcinol (Lancaster), 44.3 g (0.35 mole) of benzyl chloride, and 55.2 g (0.40 mole) of potassium carbonate in 200 ml of acetone was stirred and heated at reflux for 72 hr. The reaction mixture was filtered and the filtrate was concentrated under vacuum. The crystalline residue was recrystallized from toluene/petroleum ether to give 56.3 g (92%) of the title compound as white flakes, mp 40.5°-43.5° C.

1. temperatureheated
2. temperatureat reflux for 72 hr
3. filtrationThe reaction mixture was filtered
4. concentrationthe filtrate was concentrated under vacuum
5. customThe crystalline residue was recrystallized from toluene/petroleum ether