Toluene → HCID 11806775, compound

HRID 1494023Notes

Reaction equation

HRID 1494023 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[CH:5][C:6]([OH:9])=[CH:7][CH:8]=1.Cl[S:13]([N:16]=C=O)(=[O:15])=[O:14].C1(C)C=CC=CC=1>C1C=CC=CC=1>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[CH:5][C:6]([O:9][S:13](=[O:15])(=[O:14])[NH2:16])=[CH:7][CH:8]=1

Participants

5

Reactant 3

HCID 1140TolueneHCID 678744-(Trifluoromethyl)phenolHCID 70918Chlorosulfonyl isocyanate

Product 1

HCID 11806775HCID 11806775, compoundYield 78.7%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

This compound was prepared according to the procedure used in Example 56. A mixture of 9.6 g (0.059 mole) of α,α,α-trifluoro-p-cresol, 5.7 ml (9.2 g, 0.065 mole) of chlorosulfonyl isocyanate and 75 ml of toluene gave 11.2 g (70%) of white solid, mp 111°-112° C. (benzene).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-9ed090c411ae480b80668444eb3faa97
Source dataset
uspto-grants-1991_06
Patent number
US05025031

Reaction notes

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