4-Cyanophenol → HCID 44459430, compound

HRID 1494033Notes

Reaction equation

HRID 1494033 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1)#[N:2].Cl[S:11]([N:14]=C=O)(=[O:13])=[O:12]>C1(C)C=CC=CC=1>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([O:9][S:11](=[O:13])(=[O:12])[NH2:14])=[CH:5][CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 130194-CyanophenolHCID 70918Chlorosulfonyl isocyanate

Product 1

HCID 44459430HCID 44459430, compoundYield 51%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This compound was prepared by the procedure of Example 56 from a solution of 11.9 g (0.10 mole) of 4-cyanophenol (Aldrich Chemical Co.) and 9.1 ml (0.105 mole) of chlorosulfonyl isocyanate in 75 ml of toluene. The solid product was recrystallized from benzene-acetonitrile to give 10.1 g (51%) of white solid, mp 154°-156° C.

Workup

  1. customThe solid product was recrystallized from benzene-acetonitrile

Sources & evidence

ORD record
ord-0f0efc16fa6249b89dc4bc371eb856f1
Source dataset
uspto-grants-1991_06
Patent number
US05025031

Reaction notes

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