Water → HCID 10087643, compound

Participants

Reaction Steps

To a solution of 0.1 g (0.28 mmol) ethyl 8-azido-4-[3-(3-pyridyl)propyl]-3-thia-octanoate in 0.7 mL tetrahydrofuran is added 0.082 g triphenylphosphine followed by 0.01 mL water. The mixture is stirred at room temperature for 52 hours and then evaporated to give ethyl 8-amino-4-[3-(3-pyridyl)-propyl]-3-thia-octanoate, NMR (CDCl3) delta 4.2 (q,2H), 3.2 (s,2H).

Provenance & Evidence