HCID 54258336, compound → HCID 10317467, compound

HRID 1494133Notes

Reaction equation

HRID 1494133 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][C:10]([CH2:17][CH2:18][CH2:19][CH2:20][O:21][CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][O:23]2)=[CH:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:2]=1>C(OCC)(=O)C.[Pd]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][CH2:9][CH:10]([CH2:17][CH2:18][CH2:19][CH2:20][O:21][CH:22]2[CH2:27][CH2:26][CH2:25][CH2:24][O:23]2)[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:2]=1

Participants

4

Reactant 1

HCID 54258336HCID 54258336, compound

Product 1

HCID 10317467HCID 10317467, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1.385 g of ethyl 3-[3-(3-pyridyl)-propyl]-7-(2-tetrahydropyranyloxy)-hept-2-enoate in 30 mL ethyl acetate is hydrogenated in a Parr apparatus at 3 atmospheres pressure and room temperature in the presence of 5% Pd/C catalyst for 13 hours to yield ethyl 3-[3-(3-pyridyl)-propyl]-7-(2-tetrahydropyranyloxy)-heptanoate; NMR (CDCl3): delta 2.2 (ddd,2H).

Sources & evidence

ORD record
ord-901a702af0ae4257908e0a6a6f992e0c
Source dataset
uspto-grants-1991_06
Patent number
US05025025

Reaction notes

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